Non-contrast Measurement of Myocardial Perfusion and Oxygenation by MRI: Comparison with PET in an acute Coronary Stenotic Canine Model
Herrero P, Scott S, McCommis K, Zhang H, Zheng J, Gropler R
Washington University School of Medicine
Non-contrast quantification of myocardial blood flow (MBF) and oxygen OEF have been developed with arterial spin labeling and T2-BOLD methods. The aim of this study is to compare these novel MRI methods in the quantification of MBF and myocardial oxygen consumption (MVO2) with results obtained through PET. With an acute coronary artery stenosis in a canine model, ROI measurements of MBF and OEF by MRI were performed at rest and during dobutamine-induced stress. The MBF and MVO2 by MRI were correlated well with PET, while OEF during the stress was moderately correlated with PET result.