Combined use of endorectal MRS and apparent diffusion coefficients to increase accuracy in prostate tumour detection
Reinsberg S, Payne G, Riches S, Ashley S, deSouza N
Institute of Cancer Research, University of British Columbia
Low sensitivity and specificity of conventional imaging for prostate cancer detection can be improved by the use of combined CSI and diffusion-weighted imaging. In a study with 42 patients at 1.5T we investigate the use of a combined metabolite ratio and ADC predictor for tumour detection. At a sensitivity of 93%, specificity of detecting lesions is significantly improved for the combined predictor 91% as compared to Cho/Cit alone (73%) or ADC alone (57%). An increase in CSI resolution will minimise partial volume effects and improve tumour detection further.