Exclusion of False Positive Identification of Prostate Cancer Using Diffusion Anisotropy
Kibel A, Humphrey P, Xu J, Song S, Narra V
Washington University in St. Louis
To examine the potential utility of diffusion anisotropy in prostate cancer patient management, thirteen patients scheduled for radical prostatectomy surgery were examined by diffusion tensor imaging (DTI) in vivo. After surgery, prostate specimens were examined via ex vivo DTI, and by histology after formalin fixation. Corresponding MRI and histology findings confirm that elevated diffusion anisotropy in the central gland can facilitate differentiating benign prostatic hyperplasia from prostate cancer.