Ultra fast dynamic contrast enhanced time resolved UNFOLD imaging
Rudrapatna U, Saranathan M
Indian Institute of Science
Dynamic Contrast Enhanced (DCE) MRI has become an indispensable tool for tumor diagnostics. Any improvement in the achievable temporal resolution can be very useful, due to the trade-off between spatial and temporal resolution that exists in the current imaging schemes. This work reports a novel strategy of combining UNFOLD with time resolved imaging to effect acceleration factors of 6 and higher, thereby pushing the capabilities of DCE-MRI further. A new, computationally efficient, sinc-interpolation based reconstruction strategy has also been proposed. Tests conducted on real and simulated data validate the accuracy and increase in temporal resolution obtained using this new acquisition-reconstruction technique.