Simultaneous MRI acquisition of activation-induced change in blood flow, blood volume and blood exygenation: A human brin study
Wu W, Wong E
University of California, San Diego
Inter-scan variations such as subject motion and physiological status can complicate the interpretation of fMRI data. Yang et al recently proposed a method that combined FAIR and VASO to simultaneously acquire images with contrasts of CBV, CBF and BOLD. The optimal inversion slab thickness, however, could vary with individuals, slice orientation and flow velocity. Besides, low SNR is an inherent disadvantage of current VASO technique. Here we describe a modified sequence for the same purpose by implementing an alternative VASO technique with higher SNR and less sensitivity to inversion efficiency, at the expanse of half temporal resolution.