3T Pseudo-continuous ASL Perfusion fMRI with Background-Suppressed Single Shot 3D GRASE During Memory Encoding
Fernandez-Seara M, Wang J, Wang Z, Guenther M, Feinberg D, Detre J, Korczykowski M
University of Pennsylvania Medical Center
ASL perfusion-based fMRI was used to detect activation of the hippocampus during a memory encoding task. Perfusion data were acquired using a pseudo-continuous ASL approach combined with a background suppressed single shot 3D GRASE read-out and compared with BOLD results. Perfusion fMRI yielded stronger group activation, consistent with prior observations for sensorimotor tasks.