Comparing BOLD Resonses of TMS, Median Nerve Stimulation and Voluntary Finger Movments
Baudewig J, Kessler V, Dechent P
MR-Research in Neurology and Psychiatry, Medical Faculty, Georg-August-University
The combination of transcranial magnetic stimulation (TMS) with functional magnetic resonance imaging (fMRI) provides the possibility to directly visualize the TMS induced changes in brain activity at a high spatial and temporal resolution. Using interleaved TMS/fMRI we compared the activations shown after stimulation with TMS with the ones seen after voluntary finger movement and peripheral median nerve stimulation. Both supra- and subthreshold TMS of the primary motor cortex and median nerve stimulation resulted in the activation of cortical and subcortical structures involved in the motor network that are similar to the ones seen during voluntary thumb movement.