Quantitative Diffusion and Fat Imaging of Vertebral Compression Fractures
Kumar A, Costelloe C, LeRoux P, Ma J, Cannon B
University of Texas M. D. Anderson Cancer Center
Several published studies indicate that diffusion weighted imaging (DWI) and fat/water in-phase and opposed-phase imaging are useful in characterizing the nature of a vertebral compression fracture (VCF). In this work, we used a non-CPMG fast spin echo based diffusion technique and a spin echo based two-point Dixon technique to measure, in the same sessions, the apparent diffusion coefficient (ADC) and relative fat content in 14 cancer patients with VCFs. Our results show that between benign and malignant VCFs, the mean ADC value is statistically different. In contrast, no significant difference is found for the fat content.