3D Time-Resolved Contrast-Enhanced MRA with Sliding Subtraction
Carr J, Walker M, Hopkins J, Cashen T, Shin W, Carroll T
Northwestern University Feinberg School of Medicine
We have developed a novel 3D MR angiographic technique with high frame rate to serve as a noninvasive alternative or adjunct to X-ray DSA. 3D images were acquired of a single hemisphere of the intracranial vasculature with 1.1 x 1.1 x 2.5 mm spatial resolution and 0.3 s/frame temporal resolution after sliding window reconstruction. The sliding subtraction method yielded images with strong artery-vein separation in time, background suppression, and immunity to motion artifacts. The radial trajectory was used to provide uniform vessel enhancement without the high-pass filter effect found with Cartesian sliding window techniques.