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Abstract #0622

Quantitative MRI correlates with long-term functional outcome after traumatic brain injury in rat

Immonen R, Pitknen A, Grhn O, Kharatishvili I, Grhn H
A.I.Virtanen Institute for Molecular Sciences, University of Kuopio

Progressive tissue damage after head trauma was studied using volumetric and quantitative MRI. MRI results obtained in the acute and subacute phase 3 hours - 23 days after induction of TBI correlated with the functional outcome as assessed using Morris water maze test 7 months later. This provides evidence that MRI may facilitate the prediction of the functional outcome after TBI.