Feasibility of velocity selective arterial spin labeling in functional MRI
Bykowski J, Wu W, Wong E
University of California, San Diego
The feasibility of velocity selective arterial spin labeling (VS-ASL) has been validated in baseline CBF measurement but not in fMRI study yet. This abstract reports the discrepancy and compatibility between VS and conventional ASL fMRI in human visual cortex. Experiment results show that two techniques detect compatible spatial distribution of neuronal activation. VS-ASL further provides information of vasculature that contributes to neuronal activity from different flow direction. Meanwhile, caution has to be taken when averaging signal time curves over multiple directions of VS encoding. Flow variation during activation has negligible effect on localization (voxel size = 3.4x3.4x7 mm3).