Advances in T1-based fluid oxymetry
Dillon W, Glenn O, Manley G, Zaharchuk G, Busse R, Han E, Rosenthal G
UC San Francisco
Recent studies have shown that it is possible to measure absolute oxygen partial pressure (pO2) non-invasively in human body fluids with a dualshot nonequilibrium saturation recovery single-shot fast spin echo technique. Such a method promises insight into normal physiology as well as into changes during disease or treatment. This abstract reports mean CSF, vitreous, and bladder urine oxygenation in normal young adults. Also, potential errors due to fluid protein content and partial volume error are analyzed. Finally, the first images and measurements of pO2 in fetal CSF and vitreous in utero are presented.