MR Elastography of the Heart: Initial Feasibility
Kolipaka A, McGee K, Rossman P, Araoz P, Ehman R
Mayo Clinic, College of Medicine
Changes in the mechanical properties of myocardium are associated with a variety of cardiac disease processes. MR elastography (MRE) has been used to quantitate shear stiffness in the absence of organ motion. We hypothesize that gated acquisition sequences employed in cardiac MR can be adapted to current MRE sequences to provide shear stiffness measures of organs undergoing periodic motion. This work describes the development and initial evaluation of a gated MRE sequence in a spherical phantom undergoing period volumetric and pressure changes. The results indicate the initial feasibility of quantitating the shear stiffness of an organ undergoing these cyclic variations.