First Clinical Evaluation of Vessel Size Imaging in Human Glial Brain Tumors
Breyer T, Gall P, Kiselev V, Speck O, Mader I
Dept. of Neuroradiology
Intracranial tumors vary greatly in the extent of microvascularization, which cannot be imaged directly by current MR-techniques. The purpose of this study was to measure the vessel-size-index (VSI) in patients with glial tumors of different WHO tumor grades (II through IV), and to evaluate whether a higher tumor grade shows also an increased microvascularization. ROI analysis of normal gray matter, thalamus, normal white matter, cerebrospinal fluid and solid tumor was performed. The VSI of glial brain tumors was increased compared to normal appearing white matter, which showed smallest standard deviation.