Diffusion tensor MR imaging of the spinal cord in patients with multiple sclerosis.
OHGIYA Y, OKA M, HIWATASHI A, LIU X, KAKIMOTO N, KITAHARA T, GOKAN T, EKHOLM S, WESTESSON P
Showa University School of Medicine , University of Rochester Medical Center
we found a gradient of white matter abnormality in spinal cord extending from the plaques visible on T2-weighted imaging to the outside of the plaques in FA values. Diffusion tensor MR imaging may be more sensitive than T2-weighted imaging for assessing disease burden and monitoring effects for therapy.