Kinetic models and blood signal modeling for dynamic cardiac MRI Perfusion Studies
McGann C, Pack N, DiBella E
University of Utah
A large number of analysis methods have been used for quantitative or semi-quantitative analysis of cardiac dynamic contrast MRI data. These models are most often used without regard to signal from the blood in the tissue or from spillover of blood signal in the left ventricular blood pool. A systematic comparison of five different models, some with and some without blood signal modeling is performed. The model with the lowest error in the fit and the lowest coefficient of variation had the most parameters (5) including two for modeling signal from the blood.