Single scan acquisition of hyperpolarized 3He ventilation images and ADC images using a hybrid 2D sequence
Wild J, Teh K, Woodhouse N
University of Sheffield
A hybrid 2D ADC-ventilation sequence is presented which uses low flip angles to acquire both exams in the same breath-hold. The performance of the sequence was investigated in vivo in comparison with a conventional 2D ventilation imaging sequence. Acquisition of the ADC and ventilation images in one breath-hold provides ventilation images with comparable SNR and accurate high-resolution ADC images. The hybrid sequence used 2/3 of the gas needed for separate ADC and ventilation exams and saved the subject performing and extra breath-hold. The data is inherently registered allowing quantitative cross correlation between high spatial resolution ADC and ventilation data.