Hyperpolarized 13C MRI Cineangiography of Pulmonary Perfusion
Yu J, Ishii M, Kadlecek S, MacDuffie Woodburn J, Emami K, Rajaei S, Hammond F, Vahdat V, Rizi R, Golman K, Petersson J
University of Pennsylvania
Noninvasive measures of pulmonary perfusion may prove useful for the understanding of many physiologic and pathophysiologic conditions. In this work, we present a study of MRI cineangiogrpahy of pulmonary perfusion using a water-soluble hyperpolarized (HP) 13C MRI contrast agent- 2-hydroxyethy acyrlate. We show that HP 13C MRI is well suited to these types of studies due to its high temporal resolution, absence of background signal, and large signal to noise ratios.