MR Imaging of Ex-vivo Rat Lung with Acute Respiratory Distress Syndrome: Air-Inflation Fixation Method
Kita A, Itoh H, Kosaka N, Kimura H, Uematsu H
University of Fukui Hospital
We hypothesized that MRI could provide new information on an acute respiratory distress syndrome (ARDS) lung model using air-inflation fixation method. Seven ARDS rats were analyzed using a 1.5 T MR scanner with dual 3-inch surface coils. Lung injuries were visualized as the reticular signal increase of lung parenchyma in all subjects. The T1 and T2 values of ARDS lungs were 883.1&[plusmn]176.5 ms and 54.6&[plusmn]8.3 ms, respectively. The combination of MR imaging and the air-inflation fixation method could provide parametric information such as T1 and T2 values simultaneously with anatomical information in diffuse lung disease.