Contrast-enhanced first pass perfusion MR imaging in patients with subclinical hepatic encephalopathy
tao l, lin m, tao l
PLA General Hospital, PLA General Hospital
Subclinical hepatic encephalopathy (SHE) means the patients with hepatic disease have no obvious clinical symptoms, but characteristic neuropsychologic tests are abnormal. This study investigated 12 patients with SHE and 10 volunteers perfusion pattern in basal ganglion using GRE-EPI sequence. The CBF, CBV and MTT ratios of basal ganglion, thalamus versus ipsilateral white matter were calculated and compared with control group. The results showed the MTT values statistically reduced and CBF values statistically increased in pallidus and putamen. In conclusion, MRI is higher in temporal, spatial resolution and anatomy location than SPECT. MTT is the most sensitive perfusion parameter.