A Simple Method for the Automatic Measurement of Cortical Thickness
Bigler D, Yang Q, Smith M
Penn State College of Medicine
A simple and effective voxel-based method for measuring cortical thickness is presented that uses Euclidian distance and the gray matter output of any brain segmentation tool. The method is less calculation-intensive than surface-based techniques and is independent of the segmentation tool used. Validation was performed with images of fundamental geometric shapes and an example image of cortical thickness is demonstrated.