Multi-Parametric MR Imaging of Prostate Cancer at 3T
Chen A, Oh J, Kurhanewicz J, Xu D, Han E, Vigneron D
MR imaging and MR spectroscopic imaging utilizing endorectal coil have become important clinical tools for prostate cancer management. However, the addition of other type of MR techniques such as diffusion imaging and T2-mapping to provide quantative and functional information may improve the sensitivity and specificity of MR to characterize prostate cancer. Challenges have prevented these techniques from being clinically feasible. In this study, we developed a novel 1-hour clinical protocol combining 3T MRI, MLEV-PRESS, DTI-EPI and magnetization prepared/spiral readout T2 mapping to monitor anatomic, metabolic, and relaxivity changes in prostate cancer.