The impact of vessel motion and flow variability on MR-based wall shear rate measurement in the carotid artery
Amerom J, Macgowan C, Wu S, Al-Kwifi O, Wright G
The Hospital for Sick Children
This work investigated the effect of beat-to-beat changes in vessel position and pulsatile blood flow on MR-based measurements of wall shear rates in the carotid artery. The ECG gated phase contrast magnetic resonance images were simulated in MATLAB assuming the spatial resolution of 0.25 mm&, the inner diameter of 7 mm and circular vessel with 108.3 3.8 cm/s peak velocities. The motion and pulsation data from the in vivo measurements were integrated to the simulated k-spaces. Consequently, these factors were found to change the calculated WSR slightly (approximately 2%). This indicated that the ECG gated MR PC measurement can be an accurate method for WSR calculation in the carotid artery.