In-vivo MRSI detection of Lipid in Carotid Atherosclerotic Plaque
Boesiger P, Peters D, Schr M, Eberhardt K, Kozerke S, Yeon S
University and ETH Zrich
Proton MRSI exams with high spatial resolution were performed on five healthy volunteers and three patients with carotid atherosclerosis. Data were acquired using a periodic pulse sequence with balanced gradients and weak excitation according to the Linear Response Equilibrium approach presented recently. The exams enabled the first direct in-vivo detection of cholesterol and fatty acids in the arterial wall.