Characterization of neuro-endocrine tumors using MRI: Longitudinal study in an athymic nude mouse model
Scoazec J, Baboi L, Milot L, Pilleul F, Beuf O
Facult de Mdecine Laennec
As the main cause of treatment failure in humans, liver metastasis is an important target for therapeutic intervention. Experimental model of endocrine tumors with liver dissemination is available for evaluation of new medical therapeutics such as antiangiogenic therapy. The aim of this longitudinal study was to evaluate the performance of the detection and characterization of the liver metastases using high field MRI. The fraction of lesion over the total liver volume was quantified. Characterization of cystic or non-cystic type of lesions was achieved using various TE.