Linear Combination Filtering in White Matter With Steady-State Free Precession (SSFP) Sequences
Lim K, Mueller B, Vidarsson L, Pauly J
University of Minnesota
Myelin-water has a dramatically shorter T2 than other braintissues ( T2 &[approx] 10 to 20 ms). Prior myelin imaging methods,acquire a multi-echo dataset and then apply estimation methods toestimate the amount of short T2 signal. Theacquisition of this multi-echo dataset requires long scan times. Inthis work we use a multiple-flip angle steady state free precession(SSFP) 3D sequence for acquisition. This enables us to generatea 3D 25 slice short T2 image with a 2 x 2 x 4 mm resolution usingonly 6 min and 50 s of scantime.