Decomposition characteristics of brain tissue investigated at two different temperatures by means of 1H-MRS
Scheurer E, Ith M, Boesch C, Kreis R, Thali M
University & Inselspital Berne
Synopsis: Decomposition of brain tissue at 20C and at 4C was investigated by single voxel 1H-MRS in a sheep model over a period of 18 and 85 days, respectively. The results revealed that several metabolites show similar decomposition characteristics at both temperatures, however on a different time scale. Reproducible and unequivocal time courses of individual metabolite concentration allow for an estimation of the postmortem interval at both temperatures.