Fast T1 Mapping of the Brain at 7T with RF Calibration Using Three Point DESPOT1 Method
Li T, Deoni S
Rapid T1-maping with high resolution better than 1mm3 voxel size has great potential for clinical applications. The DESPOT1 (driven equilibrium single pulse observation of T1) approach allow accurate whole brain T1 mapping within the clinical timeframe. However, the accuracy of this method is quite sensitive to B1 inhomogeneity encountered at 7T. In this study, a modified approach based on 3 points DESPOT1 measurements is introduced, which allow rapid and high resolution T1 measurements with B1 correction in the Brain.