Toward Quantitative Whole Brain Pulsed Arterial Spin Labeling: Estimation of Transit Time with Cardiac Gating at 3T
Bodurka J, Luh W, Bandettini P
National Institutes of Health
To perform pulsed arterial spin labeling experiments of the whole brain, consideration for the tagging and timing is different from prior knowledge when tagging in the brain consist of smaller size of vessels. Due to pulsatility and fast blood velocity in the carotids and vertebrobasilar arteries, cardiac gating is required when tagging below the brain and the QUIPSS-based saturation is no longer effective. In the study, these effects are demonstrated and the transit time from tagging below the brain is estimated with pulsed ASL on a voxel-wise basis.