Mapping Dynamic Water Diffusion Process inside Human Brain based on Numerical Solution of the Diffusion Equation
Yang Y, Zhan W, Jiang L
National Institute on Drug Abuse, NIH
Water diffusion is a dynamic process existing in biological tissue. A number of diffusion MRI techniques have been developed to reveal structural information on the tissue based on water diffusion, but no technique is currently available to estimate the dynamic diffusion process of water in the whole brain. We present here a method to map the 3-D dynamic diffusion process based on a numerical solution of the diffusion equation for the entire brain, incorporating the diffusion tensor information obtained by a diffusion tensor imaging (DTI).