Improved DCE-MRI in bilateral breast imaging with fat suppressed TRICKS
Gai N, Thomasson D, Saranathan M, Gupta S, Chow C
National Institutes of Health
We have applied a modified fat suppressed TRICKS sequence for breast DCE-MRI pharmacokinetic modeling (PKM) studies. The enhanced TRICKS sequence provides improved spatial and temporal resolution which is key to improved PKM analysis. Several studies of patients at high genetic risk of breast cancer were carried out. Qualitative analysis of breast lesions show improved visibility with the new technique. Kinetic maps show increased activity in enhanced lesions for the new as well as established technique. The new technique shows greater promise for improved differentiation between malignant and benign lesions in the breast.