Study of marker component for low susceptibility tri-modalities breast tumor localization
Wang J, Holloway C, Plewes D, Li Y
Sunnybrook and Women's Health Science Centre, University of Toronto
We outline in-vitro investigations of the composition of a new breast localization marker which shows positive contrast in T1 weighted MRI, ultrasound (US) and X-ray. The marker is composed of 0.4mm diameter copper microspheres suspended in a Gd-DTPA added gel formulation. Maximum contrast in T1 weighted MRI was found with the addition of 10mmol/l Gd-DTPA. The amount of copper was used to control the US contrast do not reduce the MRI contrast of the marker. The study demonstrates the potential of the marker for use as a breast surgical localizer.