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Abstract #2986

Motion Correction for DWI with Segmented EPI: Comparison Between an Iterative Parameter Space Searching Technique and Conventional Navigator Echo Correction

Winter J, Gelman N, Thompson R
Lawson Health Research Institute, University of Western Ontario

Patient movement in multi-segment diffusion-weighted (DW) imaging generates large inter segment phase differences, which present as ghost artifacts in the final image. An iterative parameter space search was used to determine the optimal phase difference parameters for each segment of multi-segment DW EPI. Eight healthy adult volunteers and five neonatal subjects were scanned at 3.0T with a diffusion weighting of b = 600 s/mm2. The iterative phase search technique performed significantly better than motion orrection based on the conventional 1D navigator echo technique. (p< 0.005 for adults, and p<0.01 for neonates)