Implementation Of A Three-Dimensional Double Inversion-Recovery Sequence At 3 Tesla
Meara S, Barker G, Boulby P, Symms M
Institute of Psychiatry
A three-dimensional (3D) double inversion-recovery (DIR) sequence with optimised interleaved inversion has been developed to image selectively the grey matter at a magnetic field strength of 3 tesla. An optimum repetition time was derived theoretically, but it was found that other imaging parameters must be determined empirically due to magnetisation transfer effects. Typical images show that the 3D DIR sequence is successful in imaging the grey matter of the whole brain, while suppressing the signal from white matter and cerebrospinal fluid, in an acceptable scanning time. This sequence has application to diseases that affect the grey matter of the brain.