Quantitative 3D spiral 1H MRSI of the brain with an 8 channel phased-array coil
Kim D, Spielman D, Gu M
University of California at San Francisco
In brain 1H magnetic resonance spectroscopic imaging, to obtain high-quality metabolite spectra, it is important to suppress both water and lipids. However, having a residual water signal can be valuable for phasing and quantification. For 3D MRSI, it is essential to use fast imaging methods to reduce scan time while maintaining good SNR. In addition, it is desirable to have robust and efficient quantification. To achieve these goals, we implemented a 3D MRSI sequence at 1.5T with dualband spectral-spatial excitation, spiral k-space readout, 8-channel phased-array acquisition, voxel-by-voxel phasing and automated quantification using LCModel.