Abnormal Inter-hemispheric Brain Asymmetry in Adolescents with Disruptive Behavioral Disorder
Christensen J, Dunn D, Mathews V, Wang Y, Mosier K, Kalnin A, Kronenberger W
Indiana University School of Medicine, Regenstrief Institute
A new method of brain asymmetry mapping was used to detect regions of brain structural abnormality in the adolescents with disruptive behavioral disorder. Two regions in the inferior temporal lobe and the occipital/parietal region were found to have decreased asymmetry compared to normal control subjects. These regions are located along the pathway of the ventral stream of visual processing, which is involved in object recognition and visual attention. Abnormal neurodevelopmental of this neural circuitry might contribute to the cognitive dysfunction underlying disruptive behavioral.