Comparison of Arterial Spin Labeling and Dynamic Susceptibility Contrast Imaging in Glioma
Appignani B, Wong E, Hackney D, Alsop D
Beth Israel Deaconess Medical Center
T2* cerebral blood volume (CBV) and arterial spin labeling (ASL) blood flow MRI were performed in 20 studies of 18 patients with biopsy confirmed glioma. ASL and CBV relative to contralateral gray matter were significantly correlated (p<0.02). However, ASL more clearly demonstrated abnormal hemodynamics in the tumors because of greater signal to gray matter ratio and reduced large vessel and susceptibility artifacts.