Robust lipid suppression using multiple frequency-selective pulses for brain spectroscopic imaging at 3T
Gu M, Spielman D
Stanford University, Stanford University
In spectroscopic imaging, lipid signal contaminates much smaller metabolite signals, making it impossible to quantify the spectra. PRESS technique has been widely used to suppress lipids at the cost of spatial coverage. At 1.5T, inversion recovery is normally used to obtain full brain coverage with 30-40% metabolite signal loss. At 3T, frequency selective inversion recovery has been implemented to suppress lipids without causing signal loss. However, this method can not fully suppress lipids due to different T1s and B1 inhomogeneity. To address these issues, a robust lipid suppression technique has been proposed and implemented for brain spectroscopic imaging at 3T.