Diffusion-weighted MR Imaging of Ulcerative Colitis with the sensitivity encoding technique for monitoring Inflammatory Activity: Initial Experience
Haradome H, Nakamura A, Takahashi S, Ikei Y, Koyama G, Nitatori T, Honda T
Kyorin University School of Medicine
The combination of diffusion-weighted imaging (DWI) with parallel imaging has been applicable to inflammatory bowel disease. DWI is also more sensitive to inflammatory status of the tissue, than conventional MR imaging due to its realizing reflect to increasing inflammatory cell density. We evaluate the usefulness of DWI with the sensitivity encoding technique (SENSE-DWI) for detecting and monitoring colonic inflammatory activity in patients with UC in this study. Preliminary results suggest that SENSE-DWI enables to estimate site and degree of active inflammation in UC and may be useful for monitoring UC activity or assessing its therapeutic effectiveness.