Quantitative Free-Breathing Oxygen-Enhanced Imaging of the Lung
Fidler F, Jakob P, Arnold J
University of Wrzburg
Many studies of the human lung have been performed using oxygen as a contrast agent. Two major kinds of approaches were established: A T1-weighted approach and a quantitative approach based on T1-measurement. T1-weighted OE-MRI is favourable in terms of temporal and spatial resolution as well as multislice capability, but on the other hand, because only relative signal changes are detected, various undesired dependencies arise. In contrary, T1-mapping would ease standardization for routine clinical OE lung MRI. Therefore, we propose a hybrid of the T1-weighted and the T1-mapping approach which makes use of the individual advantages of both methods.