Comparison of Intraarterial MRA at 3.0T with X-ray Digital Subtraction Angiography to Detect Renal Artery Stenosis in Swine
Rhee T, Park J, Cashen T, Shin W, Schirf B, Larson A, Prasad P, Li D, Carroll T, Omary R
Northwestern University Feinberg School of Medicine
The accuracy of 3D MR angiography(MRA) of renal artery stenosis(RAS) at 1.5T using either intravenous or intraarterial(IA) gadolinium contrast injection is equivalent to digital subtraction angiography(DSA) but MRA still overestimates stenoses. We tested the hypothesis that IA MRA of RAS in swine at 3.0T was as accurate as DSA in the setting of percutaneous transluminal angioplasty(PTA). In 6 pigs, RAS measurements obtained from DSA and MRA pre-PTA(p=0.99) and post-PTA(p=0.07) were not statistically significant. Additionally, MRA measurements of RAS correlated closely to DSA measurements of RAS (r2=0.92). Thus, IA MRA of RAS in swine at 3.0T is as accurate as DSA.