Comparison of ASL kinetic curves between subjects and between brain areas
Jezzard P, Gallichan D
University of Oxford
Resting ASL data were acquired at 10 inversion times in 5 healthy subjects. Hand-drawn anatomically-based ROIs revealed distinct differences in the shape of the kinetic curve across brain regions, corresponding to the differences in structure of their feeding arteries. These regional variations show strong consistency between subjects. The data also indicate that certain regions with particularly long arrival times may not be suitable for quantitative CBF measurement at the commonly used single inversion time of 1.4s.