Fiber Tractography in Patients with Gliomas: Assessment of the extent of tumor cell infiltration in brain fiber tracts
Stadlbauer A, Salomonowitz E, Nimsky C, Buslei R, Buchfelder M, Ganslandt O
Landesklinik St. Poelten, University of Erlangen-Nuremberg
We retrospectively correlated fiber tracking using MR DT imaging with different FA threshold values and histopathological data of 25 patients with gliomas WHO grade II or III. A FA threshold of 0.15 to 0.2 seems to be best suitable to gain realistic fiber tract reconstruction around an infiltrating intrinsic brain tumor. Additionally we demonstrated potentially tumor cell infiltration of intact brain fiber tracts.