A dual-phase kinetic volume rendering approach to present 3D T1-weighted DCE-MRI data of the breast on 2D images combining morphology and kinetic characteristics.
Khazen M, Leach M
Institute of Cancer Research and The Royal Marsden NHS Foundation Trust
T1-weighted 3D dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of the breast provides an effective clinical tool for the characterization of breast cancer. One of the problems associated with DCE-MRI of the breast is distinguishing lesions from blood vessels that often display contrast agent uptake kinetics similar to many malignant tumours. Although blood vessels have characteristic shape features, these features may be difficult to assess on sectional image. We present a method to address this problem by extracting both morphologic and kinetic information from the data and producing colour-encoded volume rendering of tissue contrast agent kinetics combined with morphology.