Molecular magnetic resonance imaging of pulmonary emboli with Gadofluorine
Gunther R, Katoh M, Ruhl K, Niendorf T, Spuentrup E, Buecker A, Misselwitz B
RWTH Aachen University
Systemic application of Gadofluorine allows for selective visualization of fresh pulmonary thromboembolism in a swine model using the IR sequence. Emboli can still be visualized more than 24 hours after injection of contrast media. Although a relative high Gadolinium concentration was found, further investigation are needed to prove a specific binding. Especially the very long half life time have to be taken into account as diffusion into the clot based on high blood pool levels may also support Gd concentration within the clot.