Dependence of Concentration and Field Strength on MRI Properties of Polyvinyl Alcohol Cryogel
Wilson K, Gelman N, Orr T, Moran G, Campbell G, Thompson R
Department of Medical Biophysics, University of Western Ontario
It is not always practical or ethical to use human subjects for optimization and testing of MR pulse sequences. Thus, a tissue-mimicking phantom would be useful. Polyvinyl Alcohol Cryogel (PVA-C) has shown promise as a tissue mimicking material. By combining PVA and deionized water, heating for 2 hours and then going through a freeze thaw cycle PVA-C is produced. PVA-C was produced at several concentrations (3-30%) and a range of T1 (700-1860ms) and T2 (70-460ms) values were obtained. Using this data to match T1 and T2 properties of different tissues will allow the development of various realistic phantoms.