In-flow Effects in Determination of Arterial Input Functions
Axel L, Kim D
NYU Medical Center
Studies of dynamic contrast enhancement of tissue in MRI require accurate measurement of the arterial input function, in order to correct for the effects of contrast delivery to the tissue. If images of a large artery or the left ventricle (LV) cavity are included in the image, the blood signal can be used to approximate the arterial signal supplying the tissue. However, motion of the blood through the imaging plane may affect the signal. We sought to investigate the magnitude of this effect in the context of a representative application, studies of myocardial perfusion with first-pass contrast enhancement.