Maxim V. Terekhov1, Julien Rivoire1, Florian M. Meise1, Davide Santoro1, Wolfgang G. Schreiber1
1Department of Diagnostic and Interventional Radiology, Section of Medical Physics, Mainz University Medical School, Mainz, Germany
Apparent Diffusion Coefficient (ADC) of hyperpolarized 3He-gas in lungs is a proven method of non-invasive probing the integrity of the lungs microstructure. The essential problem of efficiency of 3He-ADC-imaging as the diagnostic tool is the poor localisation of integrity defects due to low spatial resolution of ADC-maps. The purpose of current work is to demonstrate the possibilities, provided by the phased-array parallel acquisition (32ch) for improving the efficiency of 3He ADC-measurements including creating full-3D ADC-maps. The second important task is making comparison of different methods of reconstruction the undersampled imaging datasets (e.g. mSENSE and GRAPPA) to get optimal quality ADC-image.