Charlotte Rosso1,2, Olivier Colliot2, Christine Delmaire3, Romain Valabregue3, Sylvain Baillet2, Sophie Crozier1, Didier Dormont2,4, Yves Samson1, Stphane Lehricy3,4
1Stroke Center, Pitie Salpetriere Hospital, University Pierre and Marie Curie, Paris, France; 2Cognitive neuroscience and Brain Imaging Laboratory, CNRS-UPR 640 LENA, Pitie Salpetriere Hospital, University Pierre and Marie Curie, Paris, France; 3Center for NeuroImaging Research, Pitie Salpetriere Hospital, University Pierre and Marie Curie, Paris, France; 4Department of Neuroradiology, Pitie Salpetriere Hospital, University Pierre and Marie Curie, Paris, France
We used DWI and ADC maps acquired in the first six hours of stroke onset-H6 and the day after-D1 to predict ischemic stroke outcome at three months in 76 patients. Normalized ADC maps were analyzed for differences between patients with good and poor outcome. ADC values in the corticospinal tract were measured in both groups and used to classify patients according to outcome. ADC values were lower in the CST of patients with poor than patients with good outcomes at both examinations (p<0.05). ADC values in the damaged CST predicted outcome with 65% accuracy at H6 and 71% at D1.