Hongyu An1, Andria L. Ford2, Katie Vo3, William J. Powers4, Jin-Moo Lee2, Weili Lin1
1Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; 2Neurology, Washington University in St. Louis, St. Louis, MO, USA; 3Radiology, Washington University in St. Louis, St. Louis, MO, USA; 4Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
We have utilized MR_OMI to assess the cerebral oxygen metabolic activity sequentially (<3.5 hours and at 6 hours) in hyper-acute stroke patients. By using the reperfusion and final infarct status, tissue with different outcomes (dead or alive) were examined in regions either with or without reperfusion. We found that dead tissue had much lower MR_OMI values than alive tissue independent of reperfusion status, suggesting that MR_OMI is capable of predicting tissue outcome in hyper-acute ischemic stroke.